Veratric acid

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Antagonist effects of veratric acid against UVB-induced cell damages.

Ultraviolet (UV) radiation induces DNA damage, oxidative stress, and inflammatory processes in human epidermis, resulting in inflammation, photoaging, and photocarcinogenesis. Adequate protection of skin against the harmful effect of UV irradiation is essential. In recent years naturally occurring herbal compounds such as phenolic acids, flavonoids, and high molecular weight polyphenols have ga...

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Studies in detoxication: 14. The metabolism of veratraldehyde and veratric acid in the rabbit.

The work described in this paper had two objectives. First, it was hoped that a more stable aroylglucuronide (veratroylglucuronide and anisoylglucuronide) than benzoylglucuronide (Quick, 1926; Pryde & Williams, 1933; Goebel, 1938) could be prepared for constitutional studies. In the second place, it was considered possible' that a comparative study of the metabolism of veratric acid (3:4-dimeth...

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Degradation of methoxylated benzoic acids by a Nocardia from a lignin-rich environment: significance to lignin degradation and effect of chloro substituents.

Strain A81 of Nocardia corallina hydroxylates or demethylates p-anisic acid to p-hydroxybenzoic acid and isovanillic acid. It demethylates veratric acid to a mixture of vanillic and isovanillic acids. These are both demethylated to protocatechuic acid, which undergoes ring cleavage to afford beta-carboxy-cis-cis-muconic acid. The intermediacy of protocatechuic acid in the catabolic pathway of v...

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Investigative implications of the instability and metabolism of mebeverine.

The anti-spasmodic drug mebeverine is used in the treatment of irritable bowel syndrome. It has been found to be unstable and rapidly metabolized to initially form mebeverine-alcohol and veratric acid. Mebeverine-alcohol is a precursor for a number of amphetamine-like compounds. Consequently, these, in addition to mebeverine and mebeverine-alcohol, can produce false-positive amphetamine immunoa...

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Distribution of Two bioactive compounds in flowers of Trollius chinensis.

A comprehensive procedure was established, which combined a high-performance liquid chromatography (HPLC) assay for the simultaneous quantification of 2″-O-β-L-galactopyranosylorientin (OGA) and veratric acid and a gravimetric analysis for the determination of the mass fraction of the floral parts (calyx, corolla, stalk, stamens and pistils and ovary) of Trollius chinensis, to investigate the d...

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ژورنال

عنوان ژورنال: The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science

سال: 1839

ISSN: 1941-5966,1941-5974

DOI: 10.1080/14786443908649868